ANALYSIS OF MEASURES ITEMS IN DEVELOPMENT OF INSTRUMENTS SELF-ASSESSMENT (RASCH MODELING APPLICATION)



FM1-43 is a permeant blocker of mechanosensitive ion channels in sensory neurons and inhibits behavioural responses to mechanical stimuli

Abstract The molecular identity and pharmacological properties of mechanically gated ion channels in sensory neurons are poorly understood.We show that FM1-43, a styryl dye used to fluorescently label cell membranes, permeates mechanosensitive ion channels in cultured dorsal root ganglion neurons, resulting in blockade of three previously defined s

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